Reply Orlistat and renal failure

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Conflict of Interest Statement. the Weight Management Programme Was Established with Unrestricted Educational Grants from Roche Reply—orlistat and Renal Failure Letters

Sir, We welcome the interest of MacLaughlin and Macdougall in the use of the gastrointestinal lipase inhibitor orlistat in patients with chronic kidney disease (CKD). We previously reported the rapid, non-recoverable decline of renal function in a patient with diabetic nephropathy, that coincided temporally with the successful use of orlistat for weight reduction [1]. There was histological evi...

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Orlistat, an under-recognised cause of progressive renal impairment.

Obesity is an emerging risk factor for chronic kidney disease (CKD) in the developed world. Orlistat, an intestinal lipase inhibitor, used in the treatment of obesity is available as an over-the-counter medication across the European union and in many countries worldwide. It is associated with acute kidney injury (AKI). We present three adults, followed up from 1 to 6 years, who developed de no...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2007

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfm211